Inheritance Cube: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) with 2 Resistance Alleles and maternal deposition

This is a sex-specific version of the original cube cubeHoming1RA. It assumes that the construct is on an autosome and there can be different male/female homing rates. It also has maternal deposition, i.e., when the male provides a W allele to a female with a H allele, some portion are cut during oogenesis. If the maternal deposition parameters are zero (d* parameters), this is a normal CRISPR drive.

cubeHomingDrive(
  cM = 1,
  cF = 1,
  dF = 0,
  chM = 0,
  crM = 0,
  chF = 0,
  crF = 0,
  dhF = 0,
  drF = 0,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

cM	Male homing rate
cF	Female homing rate
dF	Female deposition homing rate
chM	Male correct homing rate
crM	Male resistance generating rate
chF	Female correct homing rate
crF	Female resistance generating rate
dhF	Female correct deposition rate
drF	Female resistance deposition rate
eta	Genotype-specific mating fitness
phi	Genotype-specific sex ratio at emergence
omega	Genotype-specific multiplicative modifier of adult mortality
xiF	Genotype-specific female pupatory success
xiM	Genotype-specific male pupatory success
s	Genotype-specific fractional reduction(increase) in fertility

Value

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.