Inheritance Cube: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) with 2 Resistance Alleles and maternal deposition

This is a sex-specific version of the original cube cubeHoming1RA. It assumes that the construct is on an autosome and there can be different male/female homing rates. It also has maternal deposition, i.e., when the male provides a W allele to a female with a H allele, some portion are cut during oogenesis. If the maternal deposition parameters are zero (d* parameters), this is a normal CRISPR drive.

Usage

cubeHomingDrive(
  cM = 1,
  cF = 1,
  dF = 0,
  chM = 0,
  crM = 0,
  chF = 0,
  crF = 0,
  dhF = 0,
  drF = 0,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

cM

Male homing rate

cF

Female homing rate

dF

Female deposition homing rate

chM

Male correct homing rate

crM

Male resistance generating rate

chF

Female correct homing rate

crF

Female resistance generating rate

dhF

Female correct deposition rate

drF

Female resistance deposition rate

eta

Genotype-specific mating fitness

phi

Genotype-specific sex ratio at emergence

omega

Genotype-specific multiplicative modifier of adult mortality

xiF

Genotype-specific female pupatory success

xiM

Genotype-specific male pupatory success

s

Genotype-specific fractional reduction(increase) in fertility

Value

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.