Inheritance Cube: Homing Drive with 1 Resistance Allele

This function creates an inheritance cube to model a homing gene drive (such as a CRISPR-Cas9 system) that creates 1 type of resistance allele. It assumes no sex-specific inheritance patterns and the construct is on an autosome.

Usage

cubeHoming1RA(
  c = 1,
  ch = 0,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

c

Cutting rate

ch

Successful homing rate rate

eta

Genotype-specific mating fitness

phi

Genotype-specific sex ratio at emergence

omega

Genotype-specific multiplicative modifier of adult mortality

xiF

Genotype-specific female pupatory success

xiM

Genotype-specific male pupatory success

s

Genotype-specific fractional reduction(increase) in fertility

Value

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.